Synthesis, structure and biological activity some rare earth element complexes containing quinoline sulfonate derivatives

Vinh Nguyen Thi Ngoc, Hai Le Thi Hong

Abstract


Five new lanthanide complexes [Ln2(MeQBr-2H)3(H2O)6]. nH2O (Ln = Y, La, Pr, Nd, Eu) were synthesized by interaction between lanthanide chloride and a derivative of quinoline, namely 5-bromo-7-(carboxymethoxy)-6-hydroxy-1-methylquinolin-1-ium-3-sulfonate. The molecular formulas and structures of the complexes were determined using combination of IR, EDX, ESI MS, 1H NMR spectra, thermal analysis and single-crystal X-ray diffraction of similar compound YQBr. The results of tested antimicrobial activity showed that the complexes exhibit high activities on Bacillus subtilis, Lactobacillus fermentum with low IC50 values, 0.56÷3.55 (µg/ml).

Keywords


Lanthanide complexes; 5-bromo-7-(carboxymethoxy)-6-hydroxy-1-methylquinolin-1-ium-3-sulfonate; antibacterial activity

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References


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DOI: https://doi.org/10.51316/jca.2021.040

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